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Health Well

[Editorial] Achieving sustainable solidarity development goals

The meaning of social security varies nationally. In the USA, it might bring to mind the eponymous agency that administers social insurance providing benefits for retired individuals and those living with disability. In 1934, in the wake of the Great Depre ...

[Editorial] Dementia burden coming into focus

WHO announced the launch of the Global Dementia Observatory (GDO) on Dec 7. This new internet-focused platform aims to provide a constant monitoring service for data relating to dementia planning around the world. The GDO currently features data from 21 co ...

[Editorial] The balancing act of orphan drug pricing

In the past year, the high price tag of orphan drugs has come under severe scrutiny. Global industry players have used incentive schemes such as the USA's Orphan Drug Act (which offers a 50% tax rebate to help cover research and development costs and ...

[Comment] Offline: The unspoken dangers facing UK medical science

Hope. Clarity. Certainty. Reassurance. Don't be fooled. Brexit is not over yet. The hard part is yet to come. And many medical scientists remain anxious. A professor at one of the UK's top universities frowned. He was born in Germany and moved to ...

[Comment] Public availability of trial protocols

The Lancet has improved efforts to reduce research waste and increase the importance of scientific contributions through the Reward Campaign. One of the targets of this campaign is to make the methods of studies more accessible, which could be accomplished ...

[World Report] The cost of mass-casualty attacks

Mass-casualty attacks incur heavy human costs and impact on weakened health systems. ...

[Perspectives] Elizabeth Garrett Anderson: early pioneer of women in medicine

Today, about 55% of medical students in the UK are women. While change is needed to address issues such as the representation of women in leadership positions in medicine, career progression, and gender differences in pay and grant funding, women are now e ...

[Obituary] Joan Bicknell

Pioneering psychiatrist in learning disability. She was born in Isleworth, UK, on April 10, 1939, and died of cancer in Stalbridge, UK, on June 12, 2017, aged 78 years. ...

[Correspondence] Time for WHO to renew its commitment to health research

WHO's global Advisory Committee on Health Research (ACHR)—established in 1959 in Geneva, Switzerland, as the Advisory Committee on Medical Research (ACMR) and renamed ACHR in 1986—is one of the oldest institutions in the organisation. After establishm ...

[Correspondence] Targeted-release budesonide therapy for IgA nephropathy

Bengt Fellström and colleagues (May 27, p 2117)1 report that the addition of a targeted-release formulation of budesonide (TRF-budesonide) to an optimised renin-angiotensin system (RAS) blockade reduced proteinuria in patients with IgA nephropathy. ...

[Correspondence] Targeted-release budesonide therapy for IgA nephropathy – Authors' reply

Kenji Tsuda and colleagues correctly report that the NEFIGAN study1 investigated the use of corticosteroid therapy outside of the current guidelines,2 which endorse the use of systemic corticosteroids in patients with urinary protein excretion of more than ...

[Correspondence] Timely sensory stimulation and early childhood development

The Review by Wilson and colleagues (Dec 2, 2017)1 provides useful insights on the plight of people with or at risk of hearing loss globally, and outlines a comprehensive blueprint for intervention, especially in low-income and middle-income countries. ...

A Giant Puffing Sound

Simon Lester Ross Perot warned of a “giant sucking sound” when the original NAFTA was signed, but the new NAFTA being negotiated right now may coincide with a giant puffing sound. Marijuana legalization efforts in both Canada and the United States (and Me ...

Brexit Will Only Mean Brexit If We Regain Control of Economic Rules

Ryan Bourne The litmus test of whether “Brexit means Brexit” is if the UK has regulatory sovereignty after leaving the EU. That became clear last week, as the UK Government agreed to “full alignment with those rules of the internal market and the customs ...

Exams are eroding anaesthetic trainees’ work-life balance, college warns

Professional examinations are eroding trainees’ work-life balance, the Royal College of Anaesthetists has said.In a report on the welfare and morale of anaesthetists in training, the college said... ...

Exams are eroding anaesthetic trainees’ work-life balance, college warns

Professional examinations are eroding trainees’ work-life balance, the Royal College of Anaesthetists has said.In a report on the welfare and morale of anaesthetists in training, the college said... ...

Psychiatrist who saw patients after being told to stop practising is struck off

A former consultant psychiatrist who ignored an order from the Medical Practitioners Tribunal Service to stop practising while under investigation for misconduct has been struck off the UK medical... ...

Psychiatrist who saw patients after being told to stop practising is struck off

A former consultant psychiatrist who ignored an order from the Medical Practitioners Tribunal Service to stop practising while under investigation for misconduct has been struck off the UK medical... ...

A partially linear additive model for clustered proportion data

Proportion data with support lying in the interval [0,1] are a commonplace in various domains of medicine and public health. When these data are available as clusters, it is important to correctly incorporate the within-cluster correlation to improve the ...

FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain [RESEARCH ARTICLE]

Wai-Kit Chan, David J. Price, and Thomas Pratt ...

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