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Macular pigment and ocular biometry


Neelam K, Nolan JM, Loane E, Stack J, O'Donovan O, Au Eong KG, Beatty S

Subject Keywords: Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease
Catalogue: Systematic Reviews
Type: Report
Region: Republic of Ireland

AbstractThis study is designed to investigate the relationship between macular pigment optical density (MPOD) and ocular biometric parame-ters. The following details were recorded for 180 healthy subjects: demographic proWle; best-corrected visual acuity; refractive status; ocularbiometric parameters [axial length (AL), anterior chamber depth (ACD), lens thickness (LT) and vitreous chamber depth (VCD)]; oculardominance; MPOD; serum lutein (L) and zeaxanthin (Z). The mean MPOD (§SD) was 0.307 (0.155) and 0.305 (0.149) in the right and lefteyes, respectively. No demonstrable relationship was observed between MPOD and AL, ACD or VCD [AL: rD0.091, pD0.225; ACD:rD0.091, pD0.227; VCD: rD0.146, pD0.051]. There was a signiWcant and inverse relationship between LT and MPOD (r0.204;pD0.008), which was attenuated to non-signiWcance after correction for age and height (r0.058; pD0.466). This study fails to identifyan association between MPOD and ocular biometric parameters. This is an important negative Wnding, which allows investigators to studyMP, and its relationship with potentially important variables, without the need to correct for ocular biometric parameters.



Rights: © Public
Suggested citation:

Neelam K, Nolan JM, Loane E, Stack J, O'Donovan O, Au Eong KG, Beatty S. (2005) Macular pigment and ocular biometry [Online]. Available from: [Accessed: 19th November 2019].


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