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The evidence informingthe surgeon’s selection of intraocular lens onthe basis of light transmittance properties

Creator:

Li X. Kelly D. Nolan JM. Dennison JL. Beatty S.

Subject Keywords: Nutrition, Ageing, Older People, Mental Health, Alzheimer's Disease
Catalogue: Systematic Reviews
Type: Report
Region: Republic of Ireland
Description:

In recent years, manufacturers and distributorshave promoted commercially available intrao-cular lenses (IOLs) with transmittance proper-ties thatfilter visible short-wavelength (blue)light on the basis of a putative photoprotectiveeffect. Systematic literature review. Out of21 studies reporting on outcomes followingimplantation of blue-light-filtering IOLs (invol-ving 8914 patients and 12 919 study eyesundergoing cataract surgery), the primary out-come was vision, sleep pattern, and photopro-tection in 9 (42.9%), 9 (42.9%), and 3 (14.2%)respectively, and, of these, only 7 (33.3%) can beclassed as high as level 2b (individual cohortstudy/low-quality randomized controlled trials),all other studies being classed as level 3b orlower. Of the level 2b studies, only one (14.3%)found in favor of blue-light-filtering IOLsvsultraviolet (UV)-onlyfiltering IOLs on the basisof an association between better post-operativecontrast sensitivity (CS) at select frequencieswith the former; however, that study did notmeasure or report CS preoperatively in eithergroup, and thefinding may simply reflect betterpreoperative CS in the eyes scheduled to beimplanted with the blue-light-filtering IOL;moreover, that study failed to measure macularpigment, a natural preceptoralfilter of blue-light, augmentation of which is now known toimprove CS. In terms of photoprotection, thereis no level 2b (or higher) evidence in support ofbluefiltering IOLsvsUV-onlyfiltering IOLs.On the basis of currently available evidence,one cannot advocate for the use of blue-light-filtering IOLs over UV-onlyfiltering IOLs.

Date:

09/12/2016

Rights: © Public
Suggested citation:

Li X. Kelly D. Nolan JM. Dennison JL. Beatty S.. (2016) The evidence informingthe surgeon’s selection of intraocular lens onthe basis of light transmittance properties [Online]. Available from: http://publichealthwell.ie/node/1264169 [Accessed: 15th November 2019].

  

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Contributor:

Nutritional Research Centre Ireland (NRCI)
 
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