menu ☰
menu ˟

Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task.

Creator:

COEN, ROBERT; LAWLOR, BRIAN;

Institution: Cambridge University Press
Subject Keywords: Prospective memory; Mild cognitive impairment; Memory disorders; Neuropsychological tests; Dementia; Early detection;
Topic: Mental Health
Catalogue: Research and Evaluation
Report
Type: Article
Region: Republic of Ireland
Description:

We investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer's disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of <4/10, the Non-Specific-Non-Salient condition achieved a sensitivity = 84%, and a specificity = 95%, superior to the most discriminative RM test used (CERAD-Total Learning: sensitivity = 83%; specificity = 76%). Results suggest that PM is an early sign of memory failure in MCI-AD and may be a more pronounced deficit than retrospective failure, probably reflecting the greater self-initiated retrieval demands involved in the PM task used. Limitations include the relatively small sample size, and the use of a convenience sample (i.e. memory clinic attenders and healthy active volunteers), reducing the generalizability of the results, which should be regarded as preliminary. (JINS, 2009, 15, 154-159.).

Rights: © Public
Related: http://dx.doi.org/10.1017/S1355617708090127
Suggested citation:

COEN, ROBERT; LAWLOR, BRIAN; . () Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task. [Online]. Available from: http://publichealthwell.ie/node/632601 [Accessed: 18th October 2019].

  

View your saved citations and reading lists

Contributor:

RIAN
 
Click here to view all the resources gathered from this organisation's website.