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Beta2-agonists for exercise-induced asthma


Bonini, M., et al

Subject Keywords: Beta2-agonist, Placebo Pretreatment, Children, Adult, Exercise-induced asthma, Exercise-induced bronchoconstriction
Topic: Chronic Conditions
Chronic Conditions
Type: Article
Region: International (other)

It is well known that physical exercise can trigger asthma symptoms and can induce bronchial obstruction in people without clinical asthma. International guidelines on asthma management recommend the use of beta2-agonists at any stage of the disease. At present, however, no consensus has been reached about the efficacy and safety of beta2-agonists in the pretreatment of exercise-induced asthma and exercise-induced bronchoconstriction. For the purpose of the present review, both of these conditions are referred to by the acronymous EIA, independently from the presence of an underlying chronic clinical disease.

Physical exercise may trigger symptoms such as cough, chest tightness and shortness of breath in people with asthma that is not adequately treated (exercise-induced asthma). Sometimes people who do not have asthma still experience asthma-like symptoms during exercise; this is called exercise-induced bronchoconstriction. We looked at both types of people in this review. The treatments we were interested in are called beta2-agonists. These are drugs that are known to open up the airways (small tubes in the lungs), making it easier for people to breathe. Two kinds of beta2-agonists are available: short-acting (SABA, e.g. salbutamol and terbutaline) and long-acting (LABA, e.g. formoterol and salmeterol).



Rights: © The Cochrane Collaboration
Suggested citation:

Bonini, M., et al. (2013) Beta2-agonists for exercise-induced asthma [Online]. Available from: [Accessed: 21st September 2019].


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