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Structure and Control of Healthy Worker Effects in Studies of Pregnancy Outcomes

AbstractMuch of the literature on the healthy worker effect focuses on studies of chronic disease and mortality; however, when studying pregnancy outcomes, these effects might differ because of the short, defined risk periods of most pregnancy outcomes. Th ...

Stress Disorders and Dementia in the Danish Population

AbstractThere is an association between stress and dementia. However, less is known about dementia among persons with varied stress responses and sex differences in these associations. We used this population-based cohort study to examine dementia among pe ...

Causal Mediation Analysis With Observational Data: Considerations and Illustration Examining Mechanisms Linking Neighborhood Poverty to Adolescent Substance Use

AbstractUnderstanding the mediation mechanisms by which an exposure or intervention affects an outcome can provide a look into what has been called a “black box” of many epidemiologic associations, thereby providing further evidence of a relationship and p ...

Evaluation of the Performance of Algorithms That Use Serial Hepatitis C RNA Tests to Predict Treatment Initiation and Sustained Virological Response Among Patients Infected With Hepatitis C Virus

AbstractThe structure of electronic medical record data prevents easy population-level monitoring of hepatitis C virus (HCV) treatment uptake and cure. Using an HCV registry from a public hospital system in Atlanta, Georgia, we developed multiple algorithm ...

Mortality and Cancer Incidence in Carriers of Balanced Robertsonian Translocations: A National Cohort Study

AbstractA balanced robertsonian translocation (rob) results from fusion of 2 acrocentric chromosomes. Carriers are phenotypically normal and are often diagnosed because of recurrent miscarriages, infertility, or aneuploid offspring. Mortality and site-spec ...

Gestational Age at Arrest of Development: An Alternative Approach for Assigning Time at Risk in Studies of Time-Varying Exposures and Miscarriage

AbstractThe time between arrest of pregnancy development and miscarriage represents a window in which the pregnancy is nonviable and not developing. In effect, the pregnancy loss has already occurred, and additional exposure cannot influence its outcome. H ...

Multinomial Extension of Propensity Score Trimming Methods: A Simulation Study

AbstractCrump et al. (Biometrika. 2009;96(1):187–199), Stürmer et al. (Am J Epidemiol. 2010;172(7):843–854), and Walker et al. (Comp Eff Res. 2013;2013(3):11–20) proposed propensity score (PS) trimming methods as a means to improve efficiency (Crump) or re ...

Guideline-Based Physical Activity and Survival Among US Men With Nonmetastatic Prostate Cancer

AbstractThe survival impact of adhering to current physical activity guidelines after prostate cancer diagnosis is unknown. We therefore emulated a target trial of guideline-based physical activity interventions and 10-year survival among US men with nonme ...

Shift Work and Respiratory Infections in Health-Care Workers

AbstractRecently, there has been interest in whether shift work may enhance susceptibility to infection. Our aim was to determine whether shift workers in the health-care field have a higher incidence, duration, and/or severity of influenza-like illness (I ...

Associations Between Features of Placental Morphology and Birth Weight in Dichorionic Twins

AbstractLow birth weight is associated with perinatal and long-term morbidity and mortality, and may be a result of abnormal placental development and function. In studies of singletons, associations have been reported between features of placental morphol ...

An Investigation of Selection Bias in Estimating Racial Disparity in Stroke Risk FactorsThe REGARDS Study

AbstractSelection due to survival or attrition might bias estimates of racial disparities in health, but few studies quantify the likely magnitude of such bias. In a large national cohort with moderate loss to follow-up, we contrasted racial differences in ...

Association between diabetes, metabolic syndrome and heart attack in US adults: a cross-sectional analysis using the Behavioral Risk Factor Surveillance System 2015

Objectives Diabetes mellitus (DM) and metabolic syndrome (MS) are both associated with heart attack. Evidence regarding which condition—MS or DM—is better associated with heart attack, however, is limited. The purpose of this study is to examine DM and MS, ...

Barriers and enablers for the implementation of clinical practice guidelines in China: a mixed-method study

Objectives The aim of this study was to explore perspectives and reasoning of medical staff from Class A tertiary hospitals about the factors hindering and facilitating the uptake and use of clinical practice guidelines (CPGs) during medical procedures. De ...

Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study protocol

Introduction Endovascular thrombectomy is the standard of care for anterior circulation acute ischaemic stroke (AIS) secondary to emergent large vessel occlusion in patients who qualify. General anaesthesia (GA) or conscious sedation (CS) is usually requir ...

Evaluating the impact of cycle helmet use on severe traumatic brain injury and death in a national cohort of over 11000 pedal cyclists: a retrospective study from the NHS England Trauma Audit and Research Network dataset

Objectives In the last 10 years there has been a significant increase in cycle traffic in the UK, with an associated increase in the overall number of cycling injuries. Despite this, and the significant media, political and public health debate into this i ...

The effect of primary care availability on antibiotic consumption in Hungary: a population based panel study using unfilled general practices

Objective We analyse the effect of primary care availability on antibiotic consumption and on the quality of antibiotic prescribing behaviour. Design Retrospective panel design, secondary analysis of settlement-level administrative panel data (n=2320 settl ...

Analgesic efficacy and safety of ketamine after total knee or hip arthroplasty: a meta-analysis of randomised placebo-controlled studies

Objective To examine the analgesic efficacy and safety of ketamine after total knee or hip arthroplasty. Design Systematic review and meta-analysis. Data sources PubMed, EMBASE and Cochrane Library from inception to 22 May 2019. Eligibility criteria for se ...

Winter cancellations of elective surgical procedures in the UK: a questionnaire survey of patients on the economic and psychological impact

Objectives To quantify the economic and psychological impact of the cancellation of operations due to winter pressures on patients, their families and the economy. Design This questionnaire study was designed with the help of patient groups. Data were coll ...

Study protocol for a randomised controlled trial assessing the clinical and cost-effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care

Introduction Services are being encouraged to provide postdiagnostic treatment to those with dementia but the availability of evidence-based interventions following diagnosis has not kept pace with increase in demand. To address this need, the Journeying t ...

General practitioners predictions of their own patients health literacy: a cross-sectional study in Belgium

Objectives To support patients in their disease management, providing information that is adjusted to patients’ knowledge and ability to process health information (ie, health literacy) is crucial. To ensure effective health communication, general practiti ...

Journal Room

Peer-reviewed research articles are not included in the Health Well's catalogues which principally focus on "grey literature". 

On this page you will find summaries of research articles published in Open Access Journals and drawn down by RSS feeds from those journals . These journals cover about a quarter of all peer-reviewed journal articles and so are not comprehensive. In addition, the Health Well's topic-managers supplement these summaries with research articles from topic-related online journals.

The journal articles accessible on the Health Well website have been compiled from various sources that are not controlled by the Institute of Public Health in Ireland (IPH). IPH is therefore not responsible for the content of external websites and the inclusion of a link to an external website from the Health Well should not be understood to be an endorsement of that website.

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