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Brain and Behavior

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Attention-dependent modulation of neural activity in primary sensorimotor cortex

Abstract Although motor tasks at most times do not require much attention, there are findings that attention can alter neuronal activity not only in higher motor areas but also within the primary sensorimotor cortex. However, these findings are equivocal a ...

Issue Information

9 January 2013 Issue Information ...

2011–2012 Reviewers

9 January 2013 2011–2012 Reviewers ...

The effects of MAOA genotype, childhood trauma, and sex on trait and state-dependent aggression

9 January 2013 The effects of MAOA genotype, childhood trauma, and sex on trait and state-dependent aggression ...

Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

Abstract The combination of memantine, an N-methyl-d-aspartate (NMDA) receptor antagonist, with an acetylcholinesterase inhibitor (AChEI) is the current standard of care in Alzheimer's disease (AD). Galantamine, an AChEI currently marketed for the tre ...

HIRREM™: a noninvasive, allostatic methodology for relaxation and auto-calibration of neural oscillations

Abstract Disturbances of neural oscillation patterns have been reported with many disease states. We introduce methodology for HIRREM™ (high-resolution, relational, resonance-based electroencephalic mirroring), also known as Brainwave Optimization™, a noni ...

Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease

Abstract Cerebral dopamine neurotrophic factor (CDNF) protein has been shown to protect the nigrostriatal dopaminergic pathway when given as intrastriatal infusions in rat and mouse models of Parkinson's disease (PD). In this study, we assessed the ne ...

Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study

Abstract The lack of reliable outcome predictors and the delayed onset of therapeutic response to antidepressants are among the clinical challenges in the treatment of depression. Identifying clinical correlates associated with antidepressant response woul ...

Brain processing of pain in patients with unresponsive wakefulness syndrome

Abstract By definition, patients with unresponsive wakefulness syndrome (UWS) do not experience pain, but it is still not completely understood how far their brain can process noxious stimuli. The few positron emission tomography studies that have examined ...

Respiratory and behavioral dysfunction following loss of the GABAA receptor α4 subunit

Abstract γ-Aminobutyric acid type A (GABAA) receptor plasticity participates in mediating adaptation to environmental change. Previous studies in rats demonstrated that extrasynaptic GABAA receptor subunits and receptors in the pons, a brainstem region inv ...

Brief alcohol exposure alters transcription in astrocytes via the heat shock pathway

Abstract Astrocytes are critical for maintaining homeostasis in the central nervous system (CNS), and also participate in the genomic response of the brain to drugs of abuse, including alcohol. In this study, we investigated ethanol regulation of gene expr ...

Human hippocampal energy metabolism is impaired during cognitive activity in a lipid infusion model of insulin resistance

Abstract Neuronal glucose uptake was thought to be independent of insulin, being facilitated by glucose transporters GLUT1 and GLUT3, which do not require insulin signaling. However, it is now known that components of the insulin-mediated glucose uptake pa ...

Melatonin modulates baroreflex control via area postrema

Abstract Pineal gland and its hormone melatonin have been implicated in modulation of cardiovascular system. We aimed at studying the effects of melatonin on baroreflex sensitivity and the role of area postrema, as a component modulator of baroreflex arch. ...

Electrophysiological analysis of the role of novelty in the von Restorff effect

Abstract Items that are distinctive with respect to their context tend to be recalled better than nondistinctive items, a finding known as the von Restorff effect. The goal of this study was to elucidate the role of novelty in this effect. In two experimen ...

Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis

Abstract Sporadic and familiar amyotrophic lateral sclerosis (ALS) cases presented lower cholinergic activity than in healthy individuals in their still preserved spinal motoneurons (MNs) suggesting that cholinergic reduction might occur before MN death. T ...

Neuromagnetic activation following active and passive finger movements

Abstract The detailed time courses of cortical activities and source localizations following passive finger movement were studied using whole-head magnetoencephalography (MEG). We recorded motor-related cortical magnetic fields following voluntary movement ...

Thoracic venous congestion caused by thoracic disc herniation

Abstract We present what is to our knowledge the first reported case of thoracic disc herniation leading to venous congestive myelopathy (VCM), which was clinically and radiographically suggestive of Foix–Alajouanine syndrome (angiodysgenetic necrotizing m ...

Do not throw out the baby with the bath water: choosing an effective baseline for a functional localizer of speech processing

Abstract Speech processing engages multiple cortical regions in the temporal, parietal, and frontal lobes. Isolating speech-sensitive cortex in individual participants is of major clinical and scientific importance. This task is complicated by the fact tha ...

Social behavior is perturbed in mice after exposure to bisphenol A: a novel assessment employing an IntelliCage

Abstract In order to investigate whether or not prenatal and lactational exposure to bisphenol A (BPA) affects social behavior in mice, pregnant mice were exposed to 500 μg/kg of BPA daily from embryonic day 0 (E0) until postnatal day 21 (P21). The behavio ...

Group independent component analysis of MR spectra

Abstract This study investigates the potential of independent component analysis (ICA) to provide a data-driven approach for group level analysis of magnetic resonance (MR) spectra. ICA collectively analyzes data to identify maximally independent component ...

Journal Room

Peer-reviewed research articles are not included in the Health Well's catalogues which principally focus on "grey literature". 

On this page you will find summaries of research articles published in Open Access Journals and drawn down by RSS feeds from those journals . These journals cover about a quarter of all peer-reviewed journal articles and so are not comprehensive. In addition, the Health Well's topic-managers supplement these summaries with research articles from topic-related online journals.

The journal articles accessible on the Health Well website have been compiled from various sources that are not controlled by the Institute of Public Health in Ireland (IPH). IPH is therefore not responsible for the content of external websites and the inclusion of a link to an external website from the Health Well should not be understood to be an endorsement of that website.

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