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[Comment] Human stem cell-derived retinal cells for macular diseases

15 Oct 2014

In The Lancet, Steven Schwartz and colleagues1 report the mid-term and long-term outcomes of the use of human embryonic stem-cell (hESC)-derived retinal pigment epithelial cells for the treatment of dry atrophic age-related macular degeneration and Stargardt's macular dystrophy, the leading causes of adult and juvenile blindness in the developed world. Both eye diseases involve a disruption of the retinal pigment epithelium, a layer of cells behind the retina that helps to maintain photoreceptors and preserve the blood–retina barrier.

Click here to view the full article which appeared in The Lancet